Serotonin Receptor 1A anticorps (AA 294-312)

N° du produit ABIN617930

L’anticorps Lapin Polyclonal anti-Serotonin Receptor 1A a été validé pour IHC, IF, ICC et IEM. Il convient pour détecter Serotonin Receptor 1A dans des échantillons de Humain, Rat, Souris, Singe et Cobaye. Il y a 5+ publications disponibles.

Aperçu rapide pour Serotonin Receptor 1A anticorps (AA 294-312) (ABIN617930)

Antigène: Serotonin Receptor 1A (HTR1A)

Reactivité: Humain, Rat, Souris, Singe, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 1A est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM)

Détail du produit anti-Serotonin Receptor 1A anticorps

Épitope: AA 294-312

Réactivité croisée: Humain, Souris, Rat (Rattus)

Attributs du produit: The 5-HT 1A Receptor Antibody was raised against synthetic peptide sequence corresponding to amino acids 294-312 of the rat 5-HT1A receptor. The antiserum is provided as 100 μL of affinity purified serum containing 1 % BSA. The antiserum demonstrates strongly positive labeling of rat cortex, arcuate and hippocampus using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions are 1/100 - 1/200 in PBS - Bn/Av-HRP detection. Intensification methods such as nickel will approximately double the dilution factor as recommended. The antibody was characterized by immunohistochemistry and Western blot. Western blot showed a single band of approximately 45 kD. Preincubation of the antibody with an excess of the synthetic peptide blocked staining. Immunohistochemical staining of rat brain correlates well with Northern analysis, in situ hybridization and receptor autoradiography. BlastP database sequence homology searches confirmed that this sequence is unique to rat, mouse and human 5-HT1A receptors.

Purification: Affinity Purified

Immunogène: Rat 5-HT1A receptor (294-312)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Contains ≤ 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: After reconstitution, use immediately or refrigerate at 2 - 8 °C up to 2 days. For long-term storage aliquot antibody and freeze at -15 °C or lower. Avoid repeated freeze/thaw cycles.

Références pour anticorps anti-Serotonin Receptor 1A (ABIN617930)

Lee, Ahn, Won: "New expression of 5-HT1A receptor in astrocytes in the gerbil hippocampal CA1 region following transient global cerebral ischemia." dans: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, Vol. 36, Issue 3, pp. 383-9, (2016) (PubMed).

Wang, Wang, Zou, Qu, Liu, Fei, Xia, Needleman, Mikami, Wood: "Mast cell expression of the serotonin1A receptor in guinea pig and human intestine." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 304, Issue 10, pp. G855-63, (2013) (PubMed).

Ahn, Balaban: "Distribution of 5-HT1B and 5-HT1D receptors in the inner ear." dans: Brain research, Vol. 1346, pp. 92-101, (2010) (PubMed).

Hadjighassem, Austin, Szewczyk, Daigle, Stockmeier, Albert: "Human Freud-2/CC2D1B: a novel repressor of postsynaptic serotonin-1A receptor expression." dans: Biological psychiatry, Vol. 66, Issue 3, pp. 214-22, (2009) (PubMed).

Chalazonitis, Pham, Li, Roman, Guha, Gomes, Kan, Kessler, Gershon: "Bone morphogenetic protein regulation of enteric neuronal phenotypic diversity: relationship to timing of cell cycle exit." dans: The Journal of comparative neurology, Vol. 509, Issue 5, pp. 474-92, (2008) (PubMed).

Détails sur Serotonin Receptor 1A

Antigène: Serotonin Receptor 1A (HTR1A)

Sujet: Other Names:
5-hydroxytryptamine receptor 1A, ADRB2RL1, ADRBRL1,RAT5HT1A, 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

ID gène: 24473

Pathways: Signalistation JAK/STAT, Synaptic Membrane, Feeding Behaviour