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Macrophage Mannose Receptor 1 anticorps (APC)

MRC1 Reactivité: Humain FACS Hôte: Souris Monoclonal 15-2 APC
N° du produit ABIN6240827
  • Antigène Voir toutes Macrophage Mannose Receptor 1 (MRC1) Anticorps
    Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
    Reactivité
    • 71
    • 42
    • 23
    • 16
    • 1
    • 1
    Humain
    Hôte
    • 43
    • 30
    • 16
    Souris
    Clonalité
    • 44
    • 41
    Monoclonal
    Conjugué
    • 36
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Macrophage Mannose Receptor 1 est conjugé à/à la APC
    Application
    • 53
    • 51
    • 23
    • 16
    • 13
    • 11
    • 9
    • 9
    • 6
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody 15-2 (also known as MR15-2) recognizes an extracellular epitope of CD206 (macrophage mannose receptor, MMR), a 162-175 kDa type I transmembrane protein expressed mainly on macrophages, dendritic cells and hepatic or lymphatic endothelial cells, but not on monocytes.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Purified human mannose receptor
    Clone
    15-2
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product MRC1 Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
    Autre désignation
    CD206 (MRC1 Produits)
    Synonymes
    anticorps CD206, anticorps CLEC13D, anticorps CLEC13DL, anticorps MMR, anticorps MRC1L1, anticorps bA541I19.1, anticorps AW259686, anticorps MR, anticorps mrc1, anticorps MGC86525, anticorps MRC1, anticorps MRC1L-A, anticorps mannose receptor C-type 1, anticorps mannose receptor, C type 1, anticorps mannose receptor C-type 1 L homeolog, anticorps mediator of replication checkpoint 1, anticorps MRC1, anticorps Mrc1, anticorps mrc1.L, anticorps mrc1
    Sujet
    Mannose receptor C-type 1,CD206 (macrophage mannose receptor, MMR), also known as mannose receptor C1 (MRC1), is a type I transmembrane glycoprotein serving as pattern recognition receptor for carbogydrate groups on the surface of bacteria, fungi and other pathogens. Expressed mainly on tissue macrophages and dendritic cells, CD206 mediates endocytosis of these pathogens and presentation of their antigens to the adaptive immune system. CD206 can also be detected in a soluble form in human plasma and is elevated in patients with acute sepsis.,MMR, MRC1, CLEC13DL
    ID gène
    4360
    UniProt
    P22897
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