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MAPK6 anticorps (pSer189)

MAPK6 Reactivité: Humain IHC (p) Hôte: Lapin Polyclonal RB5800 unconjugated
N° du produit ABIN6241031
  • Antigène Voir toutes MAPK6 Anticorps
    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
    Épitope
    • 16
    • 15
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer189
    Reactivité
    • 55
    • 46
    • 27
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 62
    • 5
    • 3
    • 1
    Lapin
    Clonalité
    • 67
    • 4
    Polyclonal
    Conjugué
    • 38
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MAPK6 est non-conjugé
    Application
    • 51
    • 35
    • 18
    • 14
    • 13
    • 11
    • 8
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    C, M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This Phospho-ERK3-S189 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S189 of human ERK3.
    Clone
    RB5800
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAPK6 Anticorps primaire
  • Indications d'application
    IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Wang, Kong, Lin, Li, Izumiya, Ding, Zhang, Hu, Yang, Gao, Lam, Li: "A versatile nanoplatform for synergistic combination therapy to treat human esophageal cancer." dans: Acta pharmacologica Sinica, Vol. 38, Issue 6, pp. 931-942, (2018) (PubMed).

    Perander, Al-Mahdi, Jensen, Nunn, Kildalsen, Johansen, Gabrielsen, Keyse, Seternes: "Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2." dans: Scientific reports, Vol. 7, pp. 43471, (2017) (PubMed).

    De la Mota-Peynado, Chernoff, Beeser: "Identification of the atypical MAPK Erk3 as a novel substrate for p21-activated kinase (Pak) activity." dans: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 13603-11, (2011) (PubMed).

    Purcell, Wilkins, York, Saba-El-Leil, Meloche, Robbins, Molkentin: "Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 35, pp. 14074-9, (2007) (PubMed).

    Sakai, Yamauchi, Kawano: "[Measurement of internal voids in impression material using a digital image analyzer. Part 1. Investigation of the measurement system of a digital image analyzer]." dans: Nihon Hotetsu Shika Gakkai zasshi, Vol. 32, Issue 1, pp. 28-36, (1989) (PubMed).

  • Antigène
    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
    Autre désignation
    ERK3 (MAPK6 Produits)
    Synonymes
    anticorps ERK3, anticorps HsT17250, anticorps PRKM6, anticorps p97MAPK, anticorps 2610021I23Rik, anticorps D130053K17Rik, anticorps Erk3, anticorps Mapk4, anticorps Mapk63, anticorps Prkm4, anticorps Prkm6, anticorps ATMAPK6, anticorps ATMPK6, anticorps F18O19.10, anticorps MAP KINASE 6, anticorps MAP kinase 6, anticorps MAPK6, anticorps SUSERK3, anticorps erk3, anticorps p97mapk, anticorps si:ch211-235f12.1, anticorps mitogen-activated protein kinase 6, anticorps MAP kinase 6, anticorps MAPK6, anticorps Mapk6, anticorps MPK6, anticorps mapk6
    Sujet
    ERK3 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
    Poids moléculaire
    82681
    NCBI Accession
    NP_002739
    UniProt
    Q16659
    Pathways
    Signalisation MAPK, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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