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MAPK6 anticorps

MAPK6 Reactivité: Humain WB, ELISA, FACS Hôte: Souris Monoclonal 4-00E-08 unconjugated
N° du produit ABIN969115
  • Antigène Voir toutes MAPK6 Anticorps
    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
    Reactivité
    • 56
    • 46
    • 27
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 64
    • 4
    • 3
    • 1
    Souris
    Clonalité
    • 69
    • 3
    Monoclonal
    Conjugué
    • 38
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MAPK6 est non-conjugé
    Application
    • 50
    • 35
    • 19
    • 14
    • 13
    • 11
    • 9
    • 7
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human ERK3 expressed in E. coli.
    Clone
    4-00E-08
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Klinger, Turgeon, Lévesque, Wood, Aagaard-Tillery, Meloche: "Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 39, pp. 16710-5, (2009) (PubMed).

    Déléris, Rousseau, Coulombe, Rodier, Tanguay, Meloche: "Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5." dans: Journal of cellular physiology, Vol. 217, Issue 3, pp. 778-88, (2008) (PubMed).

  • Antigène
    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
    Autre désignation
    ERK3 (MAPK6 Produits)
    Synonymes
    anticorps ERK3, anticorps HsT17250, anticorps PRKM6, anticorps p97MAPK, anticorps 2610021I23Rik, anticorps D130053K17Rik, anticorps Erk3, anticorps Mapk4, anticorps Mapk63, anticorps Prkm4, anticorps Prkm6, anticorps ATMAPK6, anticorps ATMPK6, anticorps F18O19.10, anticorps MAP KINASE 6, anticorps MAP kinase 6, anticorps MAPK6, anticorps SUSERK3, anticorps erk3, anticorps p97mapk, anticorps si:ch211-235f12.1, anticorps mitogen-activated protein kinase 6, anticorps MAP kinase 6, anticorps MAPK6, anticorps Mapk6, anticorps MPK6, anticorps mapk6
    Sujet

    Description: The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. (provided by RefSeq) Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts

    Aliases: ERK3, PRKM6, p97MAPK, HsT17250, DKFZp686F03189, MAPK6

    Poids moléculaire
    105 kDa
    ID gène
    5597
    HGNC
    5597
    Pathways
    Signalisation MAPK, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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