ANAPC2 anticorps (C-Term)

N° du produit ABIN6242188

Cet anticorps anti-ANAPC2 Polyclonal Lapin (Clone RB51676) (ABIN6242188) détecte spécifiquement ANAPC2 dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ANAPC2 anticorps (C-Term) (ABIN6242188)

Antigène: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB51676

Détail du produit anti-ANAPC2 anticorps

Épitope: AA 712-746, C-Term

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ANAPC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 712-746 amino acids from the C-terminal region of human ANAPC2.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:25. WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur ANAPC2

Antigène: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Autre désignation: ANAPC2

Sujet: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.

Poids moléculaire: 93828

UniProt: Q9UJX6

Pathways: Regulation of Cell Size