anticorps zgc:77519, anticorps PACSIN2, anticorps DKFZp459J1025, anticorps SDPII, anticorps AI197433, anticorps sdpii, anticorps SdpII, anticorps protein kinase C and casein kinase substrate in neurons 2, anticorps protein kinase C and casein kinase substrate in neurons 2 S homeolog, anticorps pacsin2, anticorps PACSIN2, anticorps Pacsin2, anticorps pacsin2.S
Sujet
Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.