SQSTM1 anticorps (Ser351)
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- Antigène Voir toutes SQSTM1 Anticorps
- SQSTM1 (Sequestosome 1 (SQSTM1))
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Épitope
- AA 346-379, Ser351
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SQSTM1 est non-conjugé
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Application
- Western Blotting (WB)
- Homologie
- Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This Phospho-Sqstm1(S351) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 346-379 amino acids from the human region of human Phospho-Sqstm1(S351).
- Clone
- RB50742
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SQSTM1 Anticorps primaire
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- Indications d'application
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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- Antigène
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Autre désignation
- Sqstm1 (SQSTM1 Produits)
- Synonymes
- anticorps SQSTM1, anticorps sqstm1, anticorps MGC79491, anticorps A170, anticorps OSIL, anticorps PDB3, anticorps ZIP3, anticorps p60, anticorps p62, anticorps p62B, anticorps OSF-6, anticorps Osi, anticorps STAP, anticorps ZIP, anticorps sb:cb621, anticorps zgc:85784, anticorps sequestosome 1, anticorps sequestosome 1 L homeolog, anticorps SQSTM1, anticorps sqstm1, anticorps Sqstm1, anticorps sqstm1.L
- Sujet
- Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Adapter that mediates the interaction between TRAF6 and CYLD.
- Poids moléculaire
- 48163
- UniProt
- Q64337
- Pathways
- Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy
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