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SQSTM1 anticorps (Ser351)

SQSTM1 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB50742 unconjugated
N° du produit ABIN6242568
  • Antigène Voir toutes SQSTM1 Anticorps
    SQSTM1 (Sequestosome 1 (SQSTM1))
    Épitope
    • 19
    • 17
    • 15
    • 13
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 346-379, Ser351
    Reactivité
    • 150
    • 63
    • 61
    • 18
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 124
    • 24
    • 1
    • 1
    Lapin
    Clonalité
    • 126
    • 24
    Polyclonal
    Conjugué
    • 71
    • 11
    • 10
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SQSTM1 est non-conjugé
    Application
    • 101
    • 58
    • 39
    • 38
    • 22
    • 16
    • 16
    • 14
    • 14
    • 13
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This Phospho-Sqstm1(S351) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 346-379 amino acids from the human region of human Phospho-Sqstm1(S351).
    Clone
    RB50742
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SQSTM1 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    SQSTM1 (Sequestosome 1 (SQSTM1))
    Autre désignation
    Sqstm1 (SQSTM1 Produits)
    Synonymes
    anticorps SQSTM1, anticorps sqstm1, anticorps MGC79491, anticorps A170, anticorps OSIL, anticorps PDB3, anticorps ZIP3, anticorps p60, anticorps p62, anticorps p62B, anticorps OSF-6, anticorps Osi, anticorps STAP, anticorps ZIP, anticorps sb:cb621, anticorps zgc:85784, anticorps sequestosome 1, anticorps sequestosome 1 L homeolog, anticorps SQSTM1, anticorps sqstm1, anticorps Sqstm1, anticorps sqstm1.L
    Sujet
    Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Adapter that mediates the interaction between TRAF6 and CYLD.
    Poids moléculaire
    48163
    UniProt
    Q64337
    Pathways
    Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy
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