PPAP2A anticorps (C-Term)

N° du produit ABIN6242907

Détail du produit anti-PPAP2A anticorps

Antigène: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Épitope: AA 270-304, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPAP2A est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PPAP2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 270-304 amino acids from the C-terminal region of human PPAP2A.

Clone: RB51855

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur PPAP2A

Antigène: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Autre désignation: PPAP2A (PPAP2A Produits)

Synonymes: anticorps PPAP2A, anticorps wun, anticorps LLP1a, anticorps LPP1, anticorps PAP-2a, anticorps PAP2, anticorps Hic53, anticorps Hpic53, anticorps LPP-1, anticorps mPAP, anticorps PAP2A, anticorps PAP2a2, anticorps phospholipid phosphatase 1, anticorps phosphatidic acid phosphatase type 2A, anticorps phospholipid phosphatase 1 L homeolog, anticorps PLPP1, anticorps plpp1, anticorps Ppap2a, anticorps plpp1.L, anticorps Plpp1

Sujet: Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). Pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. Major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. May control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. It's down-regulation may contribute to the development of colon adenocarcinoma.

Poids moléculaire: 32156

UniProt: O14494

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway