PIP4K2A anticorps (C-Term)

N° du produit ABIN6243275

Détail du produit anti-PIP4K2A anticorps

Antigène: PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))

Épitope: AA 365-400, C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIP4K2A est non-conjugé

Application: Western Blotting (WB)

Homologie: Rat, B, H

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PIP4K2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 365-400 amino acids from the C-terminal region of human PIP4K2A.

Clone: RB51766

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur PIP4K2A

Antigène: PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))

Autre désignation: PIP4K2A (PIP4K2A Produits)

Synonymes: anticorps PI5P4KA, anticorps PIP5K2A, anticorps PIP5KII-alpha, anticorps PIP5KIIA, anticorps PIPK, anticorps AW742916, anticorps Pip5k2a, anticorps pipk, anticorps pi5p4ka, anticorps pip5k2a, anticorps pip5kiia, anticorps pip4k2a, anticorps zgc:194746, anticorps zgc:194777, anticorps phosphatidylinositol-5-phosphate 4-kinase type 2 alpha, anticorps phosphatidylinositol-5-phosphate 4-kinase, type II, alpha, anticorps phosphatidylinositol-5-phosphate 4-kinase, type II, alpha S homeolog, anticorps phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a, anticorps PIP4K2A, anticorps Pip4k2a, anticorps pip4k2a.S, anticorps pip4k2a, anticorps pip4k2aa

Sujet: Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin- stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size.

Poids moléculaire: 46225

UniProt: P48426

Pathways: Inositol Metabolic Process