TLR2 anticorps
Aperçu rapide pour TLR2 anticorps (ABIN6243378)
Antigène
Voir toutes TLR2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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Immunogène
- This TLR2 Antibody is generated from a mouse immunized with a recombinant protein .
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Isotype
- IgG1 kappa
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Indications d'application
- WB: 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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- TLR2 (Toll-Like Receptor 2 (TLR2))
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Autre désignation
- TLR2
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Sujet
- Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.
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Poids moléculaire
- 89838
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UniProt
- O60603
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
Antigène
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