HTR2A anticorps (N-Term)

N° du produit ABIN6243464

Cet anticorps Lapin Polyclonal détecte spécifiquement HTR2A dans WB et IHC (p). Il présente une réactivité envers Souris.

Aperçu rapide pour HTR2A anticorps (N-Term) (ABIN6243464)

Antigène: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTR2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB52772

Détail du produit anti-HTR2A anticorps

Épitope: AA 16-30, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Htr2a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-30 amino acids from the N-terminal region of human Htr2a.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur HTR2A

Antigène: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Autre désignation: Htr2a

Sujet: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.

Poids moléculaire: 52842

UniProt: P35363

Pathways: Signalistation JAK/STAT, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process