H2AFX anticorps (Ser139)
Aperçu rapide pour H2AFX anticorps (Ser139) (ABIN6243686)
Antigène
Voir toutes H2AFX AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 134-163, Ser139
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from human.
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Isotype
- IgG
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anti-H2A Histone Family, Member X (H2AFX) (AA 115-143), (C-Term) antibody
H2AFX Reactivité: Humain WB, IHC (p) Hôte: Souris Monoclonal 938CT5-1-1 unconjugated
anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibodyH2AFX Reactivité: Humain, Souris WB, BI Hôte: Souris Monoclonal N1-431 unconjugated
anti-H2A Histone Family, Member X (H2AFX) (H2AXS139ph) antibodyH2AFX Reactivité: Humain WB, ELISA, IF, ChIP Hôte: Lapin Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (ubLys119) antibodyH2AFX Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (pSer140) antibodyH2AFX Reactivité: Humain WB, ELISA, IHC (p), ICC, FACS, IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (H2A.XS139ph) antibodyH2AFX Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) antibodyH2AFX Reactivité: Humain WB, IHC (p) Hôte: Souris Monoclonal 8C5 unconjugated
anti-H2A Histone Family, Member X (H2AFX) (AA 1-30), (N-Term) antibodyH2AFX Reactivité: Humain WB, IHC (p) Hôte: Souris Monoclonal 980CT1-5-5 unconjugated
anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibodyH2AFX Reactivité: Humain WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (C-Term) antibodyH2AFX Reactivité: Humain WB, IF, ICC, ChIP Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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- H2AFX (H2A Histone Family, Member X (H2AFX))
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Autre désignation
- Histone H2A.X
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Sujet
- Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation.
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Poids moléculaire
- 15145
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UniProt
- P16104
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Pathways
- Telomere Maintenance, Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus
Antigène
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