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CD3 epsilon anticorps (Cytoplasmic Domain)
CD3E
Reactivité: Humain, Souris, Porc, Rat, Lapin, Boeuf (Vache), Cheval, Cobaye
FACS, WB, IF, IHC (p)
Hôte: Souris
Monoclonal
PC3-188A
unconjugated
N° du produit ABIN6252415
Détail du produit anti-CD3 epsilon anticorps
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Antigène
Voir toutes CD3 epsilon (CD3E) Anticorps
CD3 epsilon (CD3E)
Épitope
Tous les épitopes à travers CD3 epsilon Anticorps.
AA 156-168, Cytoplasmic Domain
Reactivité
Toutes les réactivités sur CD3 epsilon Anticorps
Humain, Souris, Porc, Rat, Lapin, Boeuf (Vache), Cheval, Cobaye
Hôte
Toutes les hôtes sur CD3 epsilon Anticorps
Souris
Clonalité
Toutes les clonalités sur CD3 epsilon Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CD3 epsilon Anticorps
Cet anticorp CD3 epsilon est non-conjugé
Application
Tous les applications à travers CD3 epsilon Anticorps.
Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
Protein G affinity chromatography
Immunogène
Amino acids 156-168 (cytoplasmic domain) from human CD3 epsilon chain were used as the immunogen for the CD3e antibody.
Clone
PC3-188A
Isotype
IgG1
Top Product
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Alternatives
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anti-CD3 epsilon (CD3E) (AA 156-168), (Cytoplasmic Domain) antibody
CD3E
Reactivité: Humain, Porc, Rat, Lapin, Boeuf (Vache), Cheval, Cobaye, Poulet
FACS, WB, IF
Hôte: Souris
Monoclonal
PC3-188A
unconjugated
Information d'application
(cache)
Indications d'application
WB: 1-2 μg/mL IHC (FFPE): 1-2 μg/mL for 30 min at RT Flow Cytometry: 0.5-1 μg/million cells in 0.1ml Immunofluorescence: 1-2 μg/mL Optimal dilution of the CD3e antibody should be determined by the researcher.
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Détails sur CD3 epsilon
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Antigène
CD3 epsilon (CD3E)
Autre désignation
CD3e (CD3E Produits )
Synonymes
anticorps cd3e, anticorps CD3E, anticorps t3e, anticorps tcre, anticorps AI504783, anticorps CD3, anticorps CD3epsilon, anticorps T3e, anticorps T3E, anticorps TCRE, anticorps CD3e molecule, anticorps CD3 antigen, epsilon polypeptide, anticorps cd3e, anticorps CD3E, anticorps Cd3e
Sujet
Recognizes the epsilon chain of CD3, a protein which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
ID gène
916
UniProt
P07766
Pathways
TCR Signaling , CXCR4-mediated Signaling Events , Ubiquitin Proteasome Pathway
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