MAPKAP1 anticorps (C-Term)

N° du produit ABIN6252515

Cet anticorps anti-MAPKAP1 est un anticorps Lapin Polyclonal détectant MAPKAP1 dans WB. Adapté pour Humain, Souris, Rat et Chien.

Aperçu rapide pour MAPKAP1 anticorps (C-Term) (ABIN6252515)

Antigène: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKAP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAPKAP1 anticorps

Épitope: C-Term

Purification: Protein A purified antibody

Immunogène: A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: Western blot: 1-3 μg/mL

Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur MAPKAP1

Antigène: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Autre désignation: SIN1

Sujet: MTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.

ID gène: 79109

UniProt: Q9BPZ7

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events