Phospholipase C gamma 2 anticorps (pTyr753)
Aperçu rapide pour Phospholipase C gamma 2 anticorps (pTyr753) (ABIN6256017)
Antigène
Voir toutes Phospholipase C gamma 2 (PLCG2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr753
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Specificité
- Phospho-PLCG2 (Tyr753) Antibody detects endogenous levels of PLCG2 only when phosphorylated at Tyrosine 753.
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Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogène
- A synthesized peptide derived from human PLCG2 around the phosphorylation site of Tyr753.
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- Phospholipase C gamma 2 (PLCG2)
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Autre désignation
- PLCG2
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Sujet
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Description: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Gene: PLCG2
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Poids moléculaire
- 150kDa
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ID gène
- 5336
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UniProt
- P16885
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Pathways
- Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
Antigène
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