5HT1B Receptor anticorps (Internal Region)

N° du produit ABIN6256875

L’anticorps anti-5HT1B Receptor Polyclonal Lapin est utilisé pour la détection de 5HT1B Receptor dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IHC, IF et ICC.

Aperçu rapide pour 5HT1B Receptor anticorps (Internal Region) (ABIN6256875)

Antigène: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 5HT1B Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-5HT1B Receptor anticorps

Épitope: Internal Region

Fonction: 5HT1B Receptor Antibody

Specificité: 5HT1B Receptor Antibody detects endogenous levels of total 5HT1B Receptor.

Homologie: Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human 5HT1B Receptor, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur 5HT1B Receptor

Antigène: 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))

Autre désignation: 5HT1B Receptor

Sujet:

Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.

Gene: HTR1B

Poids moléculaire: 44 kDa

ID gène: 3351

UniProt: P28222

Pathways: Signalistation JAK/STAT, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteins