MYO9B anticorps (N-Term)

N° du produit ABIN6257337

Détail du produit anti-MYO9B anticorps

Antigène: MYO9B (Myosin IXB (MYO9B))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYO9B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: MYO9B Antibody detects endogenous levels of total MYO9B.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MYO9B, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MYO9B

Antigène: MYO9B (Myosin IXB (MYO9B))

Autre désignation: MYO9B (MYO9B Produits)

Synonymes: anticorps CELIAC4, anticorps MYR5, anticorps MYO9B, anticorps fb53f01, anticorps wu:fb53f01, anticorps wu:fc47c07, anticorps si:dkeyp-66d1.8, anticorps myosin IXB, anticorps myosin IXb, anticorps unconventional myosin-IXb, anticorps MYO9B, anticorps Myo9b, anticorps myo9b, anticorps LOC100450445

Sujet:

Description: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions (PubMed:9490638). Also acts as a GTPase activator for RHOA (PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1, interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257).

Gene: MYO9B

Poids moléculaire: 250 kDa

ID gène: 4650

UniProt: Q13459