CITED2 anticorps (Internal Region)

N° du produit ABIN6258022

Détail du produit anti-CITED2 anticorps

Antigène: CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CITED2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: CITED2 Antibody detects endogenous levels of total CITED2.

Homologie: Pig,Bovine,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CITED2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur CITED2

Antigène: CITED2 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2))

Autre désignation: CITED2 (CITED2 Produits)

Synonymes: anticorps mrg1, anticorps p35srj, anticorps zgc:103418, anticorps CITED2, anticorps cite2, anticorps ASD8, anticorps MRG-1, anticorps MRG1, anticorps P35SRJ, anticorps VSD2, anticorps AI835299, anticorps ER154-like, anticorps Mrg1, anticorps Msg2, anticorps Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2, anticorps Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2, anticorps Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2, anticorps Cbp/p300-interacting transactivator 2, anticorps Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2 L homeolog, anticorps cited2, anticorps CITED2, anticorps cite2, anticorps Cited2, anticorps cited2.L

Sujet:

Description: Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor, interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis, potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP), stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region.

Gene: CITED2

Poids moléculaire: 28 kDa

ID gène: 10370

UniProt: Q99967

Pathways: Tube Formation