GRIN2D anticorps (Internal Region)

N° du produit ABIN6258225

Détail du produit anti-GRIN2D anticorps

Antigène: GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIN2D est non-conjugé

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: GRIN2D Antibody detects endogenous levels of total GRIN2D.

Homologie: Pig,Bovine,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human GRIN2D, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur GRIN2D

Antigène: GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))

Autre désignation: GRIN2D (GRIN2D Produits)

Synonymes: anticorps nr2d, anticorps EB11, anticorps GluN2D, anticorps NMDAR2D, anticorps NR2D, anticorps glutamate ionotropic receptor NMDA type subunit 2D, anticorps glutamate receptor, ionotropic, N-methyl D-aspartate 2D, anticorps glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog, anticorps glutamate receptor, ionotropic, NMDA2D (epsilon 4), anticorps GRIN2D, anticorps grin2d.L, anticorps grin2d, anticorps Grin2d

Sujet:

Description: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:9489750, PubMed:27616483, PubMed:26875626, PubMed:28126851). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:9489750).

Gene: GRIN2D

Poids moléculaire: 170 kDa

ID gène: 2906

UniProt: O15399

Pathways: Synaptic Membrane