GPR31 anticorps (Internal Region)

N° du produit ABIN6258802

Détail du produit anti-GPR31 anticorps

Antigène: GPR31 (G Protein-Coupled Receptor 31 (GPR31))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR31 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: GPR31 Antibody detects endogenous levels of total GPR31.

Homologie: Pig,Bovine,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human GPR31, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur GPR31

Antigène: GPR31 (G Protein-Coupled Receptor 31 (GPR31))

Autre désignation: GPR31 (GPR31 Produits)

Synonymes: anticorps 12-HETER, anticorps HETER, anticorps HETER1, anticorps GPR31, anticorps GPR31c(t), anticorps Gpr31, anticorps Gpr31c, anticorps G protein-coupled receptor 31, anticorps G protein-coupled receptor 31, D17Leh66b region, anticorps GPR31, anticorps Gpr31, anticorps Gpr31b

Sujet:

Description: High-affinity receptor for 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.

Gene: GPR31

Poids moléculaire: 33 kDa

ID gène: 2853

UniProt: O00270