SGK3 anticorps (C-Term)

N° du produit ABIN6258948

Détail du produit anti-SGK3 anticorps

Antigène: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGK3 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: SGK3 Antibody detects endogenous levels of total SGK3.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SGK3, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur SGK3

Antigène: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Autre désignation: SGK3 (SGK3 Produits)

Synonymes: anticorps CISK, anticorps SGK2, anticorps SGKL, anticorps 2510015P22Rik, anticorps A330005P07Rik, anticorps Cisk, anticorps fy, anticorps fz, anticorps Sgkl, anticorps zgc:162253, anticorps serum/glucocorticoid regulated kinase family member 3, anticorps serum/glucocorticoid regulated kinase 3, anticorps serum/glucocorticoid regulated kinase family, member 3, anticorps serine/threonine-protein kinase Sgk3, anticorps SGK3, anticorps Sgk3, anticorps LOC464217, anticorps sgk3, anticorps LOC100231693, anticorps LOC100343709, anticorps LOC100052030, anticorps LOC100521447

Sujet:

Description: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na+ channels: SCNN1A/ENAC and SCN5A, K+ channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca2+ channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na+/dicarboxylate cotransporter: SLC13A2/NADC1, Na+-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na+/H+ exchanger: SLC9A3/NHE3, and the Na+/K+ ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes.

Gene: SGK3

Poids moléculaire: 57 kDa

ID gène: 100533105, 23678

UniProt: Q96BR1