FIL1d anticorps (Internal Region)

N° du produit ABIN6259266

Détail du produit anti-FIL1d anticorps

Antigène: FIL1d (Interleukin 1 delta (FIL1d))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FIL1d est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: IL1F5 Antibody detects endogenous levels of total IL1F5.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human IL1F5, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur FIL1d

Antigène: FIL1d (Interleukin 1 delta (FIL1d))

Autre désignation: IL36RN (FIL1d Produits)

Synonymes: anticorps AI413231, anticorps Fil1delta, anticorps IL36RN, anticorps Il-1h3, anticorps Il1hy1, anticorps FIL1, anticorps FIL1(DELTA), anticorps FIL1D, anticorps IL1F5, anticorps IL1HY1, anticorps IL1L1, anticorps IL1RP3, anticorps IL36RA, anticorps PSORP, anticorps Il1f5, anticorps interleukin 1 family, member 5 (delta), anticorps interleukin 36 receptor antagonist, anticorps Il1f5, anticorps IL36RN, anticorps Il36rn

Sujet:

Description: Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response, similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Gene: IL36RN

Poids moléculaire: 17 kDa

ID gène: 26525

UniProt: Q9UBH0