SMG7 anticorps (Internal Region)

N° du produit ABIN6259540

Détail du produit anti-SMG7 anticorps

Antigène: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMG7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Specificité: SMG7 Antibody detects endogenous levels of total SMG7.

Homologie: Pig,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SMG7, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SMG7

Antigène: SMG7 (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))

Autre désignation: SMG7 (SMG7 Produits)

Synonymes: anticorps 9430023P16Rik, anticorps mKIAA0250, anticorps C1orf16, anticorps EST1C, anticorps SGA56M, anticorps Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), anticorps SMG7, nonsense mediated mRNA decay factor, anticorps Smg7, anticorps SMG7

Sujet:

Description: Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.

Gene: SMG7

Poids moléculaire: 127 kDa

ID gène: 9887

UniProt: Q92540