APOBR anticorps (C-Term)

N° du produit ABIN6259983

Détail du produit anti-APOBR anticorps

Antigène: APOBR (Apolipoprotein B Receptor (APOBR))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOBR est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: APOB48R Antibody detects endogenous levels of total APOB48R.

Homologie: Pig,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human APOB48R, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur APOBR

Antigène: APOBR (Apolipoprotein B Receptor (APOBR))

Autre désignation: APOBR (APOBR Produits)

Synonymes: anticorps APOB48R, anticorps Apob-48r, anticorps Apob48r, anticorps RGD1565169, anticorps APOB100R, anticorps apolipoprotein B receptor, anticorps apolipoprotein B48 receptor, anticorps APOBR, anticorps LOC745786, anticorps Apobr

Sujet:

Description: Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.

Gene: APOBR

Poids moléculaire: 115 kDa

ID gène: 55911

UniProt: Q0VD83