CDT1 anticorps (C-Term)

N° du produit ABIN6260731

Détail du produit anti-CDT1 anticorps

Antigène: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDT1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: CDT1 Antibody detects endogenous levels of total CDT1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CDT1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CDT1

Antigène: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Autre désignation: CDT1 (CDT1 Produits)

Synonymes: anticorps CDT1, anticorps fc37h07, anticorps im:7158083, anticorps wu:fc37h07, anticorps wu:fi38h09, anticorps xcdt1, anticorps DUP, anticorps RIS2, anticorps 2610318F11Rik, anticorps AW545653, anticorps C76791, anticorps Ris2, anticorps dup, anticorps ris2, anticorps chromatin licensing and DNA replication factor 1, anticorps chromatin licensing and DNA replication factor 1 L homeolog, anticorps CDT1, anticorps cdt1, anticorps Cdt1, anticorps cdt1.L

Sujet:

Description: Required for both DNA replication and mitosis (PubMed:11125146, PubMed:22581055, PubMed:21856198, PubMed:14993212, PubMed:26842564). DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC)(PubMed:14672932). Required also for mitosis by promoting stable kinetochore-microtubule attachments (PubMed:22581055). Potential oncogene (By similarity).

Gene: CDT1

Poids moléculaire: 63 kDa

ID gène: 81620

UniProt: Q9H211

Pathways: Signalisation MAPK, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA