CDT1 anticorps (C-Term)

N° du produit ABIN7453476

Détail du produit anti-CDT1 anticorps

Antigène: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDT1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-CDT1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 500 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:1,000 - 1:2,500

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CDT1

Antigène: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Autre désignation: CDT1 (CDT1 Produits)

Synonymes: anticorps CDT1, anticorps fc37h07, anticorps im:7158083, anticorps wu:fc37h07, anticorps wu:fi38h09, anticorps xcdt1, anticorps DUP, anticorps RIS2, anticorps 2610318F11Rik, anticorps AW545653, anticorps C76791, anticorps Ris2, anticorps dup, anticorps ris2, anticorps chromatin licensing and DNA replication factor 1, anticorps chromatin licensing and DNA replication factor 1 L homeolog, anticorps CDT1, anticorps cdt1, anticorps Cdt1, anticorps cdt1.L

Sujet: Background: CDT1 is involved in the formation of pre-replicative complexes (preRC) at origins of replication. Under tight regulation, CDT1 associates with chromatin during G1 in a dynamic manner to promote the loading of mini-chromosome maintenance (MCM) complex in preparation for replication. CDT1 is negatively regulated by ubiquitin-directed degradation and has been demonstrated to be protected from ubiquitination by the protein geminin.

ID gène: 81620

NCBI Accession: NP_112190

UniProt: Q9H211

Pathways: Signalisation MAPK, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA