CHI3L1 anticorps (Internal Region)

N° du produit ABIN6260804

Détail du produit anti-CHI3L1 anticorps

Antigène: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHI3L1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: CHI3L1 Antibody detects endogenous levels of total CHI3L1.

Homologie: Pig,Bovine,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CHI3L1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:100, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CHI3L1

Antigène: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Autre désignation: CHI3L1 (CHI3L1 Produits)

Synonymes: anticorps AW208766, anticorps Brp39, anticorps Gp39, anticorps ASRT7, anticorps CGP-39, anticorps GP-39, anticorps GP39, anticorps HC-gp39, anticorps HCGP-3P, anticorps YKL-40, anticorps YKL40, anticorps YYL-40, anticorps hCGP-39, anticorps GP38K, anticorps CLP-1, anticorps SPC-40, anticorps SPS-40, anticorps Chil1, anticorps BP40, anticorps MGP-40, anticorps chitinase-like 1, anticorps chitinase 3 like 1, anticorps chitinase 3-like 1 (cartilage glycoprotein-39), anticorps Chil1, anticorps CHI3L1, anticorps Chi3l1

Classe de substances: Viral Protein

Sujet:

Description: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

Gene: CHI3L1

Poids moléculaire: 43kD

ID gène: 1116

UniProt: P36222