CTH anticorps (N-Term)

N° du produit ABIN6261082

Détail du produit anti-CTH anticorps

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTH est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: CTH Antibody detects endogenous levels of total CTH.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CTH, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CTH

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Autre désignation: CTH (CTH Produits)

Synonymes: anticorps DYT17, anticorps DYT18, anticorps DYT9, anticorps EIG12, anticorps GLUT, anticorps GLUT1, anticorps GLUT1DS, anticorps HTLVR, anticorps PED, anticorps wu:fb48e03, anticorps wu:fb58d08, anticorps zgc:66001, anticorps zgc:85785, anticorps CTH, anticorps 0610010I13Rik, anticorps AI314617, anticorps BC019483, anticorps CSE, anticorps Cys3, anticorps cysA, anticorps SCQ11.03c, anticorps DDBDRAFT_0190313, anticorps DDBDRAFT_0191318, anticorps DDB_0190313, anticorps DDB_0191318, anticorps H, anticorps MGC75946, anticorps cystathionine gamma-lyase, anticorps solute carrier family 2 member 1, anticorps cystathionase (cystathionine gamma-lyase), anticorps cystathionine gamma-lyase L homeolog, anticorps CTH, anticorps SLC2A1, anticorps cth, anticorps Cth, anticorps SCO3920, anticorps mlr1566, anticorps TA_RS00415, anticorps MAP_RS15640, anticorps SPO3344, anticorps CNN01730, anticorps Mmcs_1928, anticorps RHA1_RS31820, anticorps HNE_1212, anticorps MAV_3867, anticorps MSMEG_2394, anticorps Mvan_2142, anticorps SACE_6136, anticorps Mflv_4220, anticorps cysA, anticorps cth.L

Sujet:

Description: Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.

Gene: CTH

Poids moléculaire: 45 kDa

ID gène: 1491

UniProt: P32929

Pathways: ER-Nucleus Signaling, L'effet Warburg