CXXC5 anticorps

N° du produit ABIN6261130

Détail du produit anti-CXXC5 anticorps

Antigène: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXXC5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: CXXC5 antibody detects endogenous levels of CXXC5.

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CXXC5.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur CXXC5

Antigène: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Autre désignation: CXXC5 (CXXC5 Produits)

Synonymes: anticorps 4930415K17Rik, anticorps CF5, anticorps RINF, anticorps WID, anticorps CXXC finger 5, anticorps CXXC finger protein 5, anticorps Cxxc5, anticorps CXXC5

Sujet:

Description: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4 % oxygen), as well as normoxia conditions (20 % oxygen) (PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788).

Gene: CXXC5

Poids moléculaire: 35-40 kDa

ID gène: 51523

UniProt: Q7LFL8