FAF2 anticorps (Internal Region)

N° du produit ABIN6261659

Détail du produit anti-FAF2 anticorps

Antigène: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: FAF2 Antibody detects endogenous levels of total FAF2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human FAF2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur FAF2

Antigène: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Autre désignation: FAF2 (FAF2 Produits)

Synonymes: anticorps FAF2, anticorps UBXD8, anticorps ETEA, anticorps UBXN3B, anticorps 2210404D11Rik, anticorps AI462440, anticorps Ubxd8, anticorps mKIAA0887, anticorps 2210404d11rik, anticorps RGD1306577, anticorps UBX8, anticorps etea, anticorps ubxd8, anticorps ubxn3b, anticorps Fas associated factor family member 2, anticorps Fas associated factor family member 2 S homeolog, anticorps FAF2, anticorps Faf2, anticorps faf2.S

Sujet:

Description: Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:18711132, PubMed:24215460). By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway (PubMed:26692333). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis (PubMed:23297223).

Gene: FAF2

Poids moléculaire: 53 kDa

ID gène: 23197

UniProt: Q96CS3