HOMER1 anticorps (Internal Region)

N° du produit ABIN6262337

Détail du produit anti-HOMER1 anticorps

Antigène: HOMER1 (Homer Homolog 1 (HOMER1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOMER1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: HOMER1 Antibody detects endogenous levels of total HOMER1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HOMER1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur HOMER1

Antigène: HOMER1 (Homer Homolog 1 (HOMER1))

Autre désignation: HOMER1 (HOMER1 Produits)

Synonymes: anticorps HOMER, anticorps HOMER1A, anticorps HOMER1B, anticorps HOMER1C, anticorps SYN47, anticorps Ves-1, anticorps HOMER1, anticorps PSD-Zip45, anticorps homer1, anticorps zgc:100854, anticorps zgc:92844, anticorps HOMER1F, anticorps Vesl-1, anticorps homer, anticorps xhomer1, anticorps BEST:LD03829, anticorps CG11324, anticorps Dhom, anticorps Dhomer, anticorps Dm Homer, anticorps Dmel\CG11324, anticorps Dvh, anticorps Hom, anticorps Homer, anticorps LD03829, anticorps dhom, anticorps homer scaffolding protein 1, anticorps homer scaffolding protein 1b, anticorps homer scaffolding protein 1 L homeolog, anticorps CG11324 gene product from transcript CG11324-RD, anticorps HOMER1, anticorps Homer1, anticorps homer1b, anticorps homer1.L, anticorps homer

Sujet:

Description: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.

Gene: HOMER1

Poids moléculaire: 46-48 kDa

ID gène: 9456

UniProt: Q86YM7

Pathways: Skeletal Muscle Fiber Development