HSD17B12 anticorps (Internal Region)

N° du produit ABIN6262377

Détail du produit anti-HSD17B12 anticorps

Antigène: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B12 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: HSD17B12 Antibody detects endogenous levels of total HSD17B12.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HSD17B12, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur HSD17B12

Antigène: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Autre désignation: HSD17B12 (HSD17B12 Produits)

Synonymes: anticorps KAR, anticorps SDR12C1, anticorps 2610510O05Rik, anticorps AI172963, anticorps KIK-I, anticorps Kik1, anticorps HSD17B12, anticorps kar, anticorps sdr12c1, anticorps 17-beta-HSD 12-A, anticorps fi06g11, anticorps wu:fi06g11, anticorps zf3.1, anticorps zfHSD17B12A, anticorps zgc:55589, anticorps zgc:77599, anticorps hydroxysteroid 17-beta dehydrogenase 12, anticorps hydroxysteroid (17-beta) dehydrogenase 12, anticorps hydroxysteroid (17-beta) dehydrogenase 12 L homeolog, anticorps hydroxysteroid (17-beta) dehydrogenase 12a, anticorps HSD17B12, anticorps Hsd17b12, anticorps hsd17b12.L, anticorps hsd17b12a

Sujet:

Description: Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.

Gene: HSD17B12

Poids moléculaire: 34 kDa

ID gène: 51144

UniProt: Q53GQ0

Pathways: Steroid Hormone Biosynthesis