MDM4-binding Protein anticorps (Internal Region)

N° du produit ABIN6263182

Cet anticorps anti-MDM4-binding Protein Polyclonal Lapin (ABIN6263182) détecte spécifiquement MDM4-binding Protein dans WB, ELISA, IHC, IF et ICC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MDM4-binding Protein anticorps (Internal Region) (ABIN6263182)

Antigène: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDM4-binding Protein est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-MDM4-binding Protein anticorps

Épitope: Internal Region

Specificité: MDM4 Antibody detects endogenous levels of total MDM4.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MDM4, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MDM4-binding Protein

Antigène: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Autre désignation: MDM4

Sujet:

Description: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Gene: MDM4

Poids moléculaire: 55 kDa

ID gène: 4194

UniProt: O15151

Pathways: Cycle Cellulaire