NFAM1 anticorps (Internal Region)

N° du produit ABIN6263620

Détail du produit anti-NFAM1 anticorps

Antigène: NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFAM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: NFAM1 Antibody detects endogenous levels of total NFAM1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NFAM1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur NFAM1

Antigène: NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))

Autre désignation: NFAM1 (NFAM1 Produits)

Synonymes: anticorps 4921501M20Rik, anticorps Cnaip, anticorps CNAIP, anticorps bK126B4.4, anticorps RGD1308316, anticorps NFAT activating protein with ITAM motif 1, anticorps Nfat activating molecule with ITAM motif 1, anticorps NFAM1, anticorps Nfam1

Sujet:

Description: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.

Gene: NFAM1

Poids moléculaire: 30kDa

ID gène: 150372

UniProt: Q8NET5