LEPREL2 anticorps (Internal Region)

N° du produit ABIN6263960

Détail du produit anti-LEPREL2 anticorps

Antigène: LEPREL2 (Leprecan Like Protein 2 (LEPREL2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LEPREL2 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Specificité: P3H3 Antibody detects endogenous levels of total P3H3.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human P3H3, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur LEPREL2

Antigène: LEPREL2 (Leprecan Like Protein 2 (LEPREL2))

Autre désignation: P3H3 (LEPREL2 Produits)

Synonymes: anticorps GRCB, anticorps HSU47926, anticorps P3H3, anticorps BC016431, anticorps Grcb, anticorps P3h3, anticorps prolyl 3-hydroxylase 3, anticorps P3H3, anticorps P3h3

Sujet:

Description: Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Required for normal hydroxylation of lysine residues in type I collagen chains in skin, bone, tendon, aorta and cornea. Required for normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly. Apparently not required for normal prolyl 3-hydroxylation on collagen chains, possibly because it functions redundantly with other prolyl 3-hydroxylases.

Gene: P3H3

Poids moléculaire: 82 kDa

ID gène: 10536

UniProt: Q8IVL6