Patched 1 anticorps

N° du produit ABIN6264047

Cet anticorps Lapin Polyclonal détecte spécifiquement Patched 1 dans WB, ELISA, IF, ICC et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Patched 1 anticorps (ABIN6264047)

Antigène: Patched 1 (PTCH1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Patched 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Patched 1 anticorps

Specificité: Patched Antibody detects endogenous levels of total Patched

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Patched

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC-p 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur Patched 1

Antigène: Patched 1 (PTCH1)

Autre désignation: Patched

Sujet:

Description: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

Gene: PTCH1

ID gène: 5727

UniProt: Q13635

Pathways: Signalisation Hedgehog, Carbohydrate Homeostasis, Tube Formation