PSMB9 anticorps (Internal Region)

N° du produit ABIN6264478

Détail du produit anti-PSMB9 anticorps

Antigène: PSMB9 (Proteasome (Prosome, Macropain) Subunit, beta Type, 9 (Large Multifunctional Peptidase 2) (PSMB9))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMB9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: Proteasome 20S LMP2 Antibody detects endogenous levels of total Proteasome 20S LMP2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Proteasome 20S LMP2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-PSMB9 (ABIN6264478)

Liu, Wu, Zhu, Li, Liu: "IRG1 increases MHC class I level in macrophages through STAT-TAP1 axis depending on NADPH oxidase mediated reactive oxygen species." dans: International immunopharmacology, Vol. 48, pp. 76-83, (2018) (PubMed).

Détails sur PSMB9

Antigène: PSMB9 (Proteasome (Prosome, Macropain) Subunit, beta Type, 9 (Large Multifunctional Peptidase 2) (PSMB9))

Autre désignation: PSMB9 (PSMB9 Produits)

Synonymes: anticorps LMP2, anticorps ring12, anticorps MHC-linked, anticorps psmb9b, anticorps lmp2, anticorps lmp2b, anticorps psmb9, anticorps Lmp-2, anticorps Lmp2, anticorps PSMB6i, anticorps RING12, anticorps beta1i, anticorps psmb9-A, anticorps macropain, anticorps prosome, anticorps wu:fa66f04, anticorps wu:fj22d05, anticorps zgc:91842, anticorps psmb9a, anticorps proteasome subunit beta 9, anticorps LMP2, anticorps proteasome subunit beta type-9b, anticorps proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2), anticorps proteasome subunit beta 9 S homeolog, anticorps proteasome subunit beta 9a, anticorps proteasome (prosome, macropain) subunit, beta type, 9a, anticorps psmb9, anticorps PSMB9, anticorps psmb9-b, anticorps Psmb9, anticorps psmb9.S, anticorps psmb9a

Sujet:

Description: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic  pH . The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues.

Gene: PSMB9

Poids moléculaire: 23kDa

ID gène: 5698

UniProt: P28065

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA