RQCD1 anticorps (Internal Region)

N° du produit ABIN6264862

Détail du produit anti-RQCD1 anticorps

Antigène: RQCD1 (RCD1 Required For Cell Differentiation1 Homolog (RQCD1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RQCD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: RQCD1 Antibody detects endogenous levels of total RQCD1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RQCD1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur RQCD1

Antigène: RQCD1 (RCD1 Required For Cell Differentiation1 Homolog (RQCD1))

Autre désignation: CNOT9 (RQCD1 Produits)

Synonymes: anticorps 2610007F23Rik, anticorps AI593551, anticorps Fl10, anticorps CNOT9, anticorps CT129, anticorps RCD-1, anticorps RCD1, anticorps wu:fb52b11, anticorps wu:fb74e08, anticorps zgc:85618, anticorps CCR4-NOT transcription complex, subunit 9, anticorps CCR4-NOT transcription complex subunit 9, anticorps Cnot9, anticorps CNOT9, anticorps cnot9

Sujet:

Description: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.

Gene: CNOT9

Poids moléculaire: 34-40 kDa

ID gène: 9125

UniProt: Q92600

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling