SCARB1 anticorps (Internal Region)

N° du produit ABIN6264935

Cet anticorps Lapin Polyclonal détecte spécifiquement SCARB1 dans WB, ELISA, IHC, IF et ICC. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour SCARB1 anticorps (Internal Region) (ABIN6264935)

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCARB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-SCARB1 anticorps

Épitope: Internal Region

Specificité: SCARB1 Antibody detects endogenous levels of total SCARB1.

Homologie: Pig,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human SCARB1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SCARB1

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Autre désignation: SCARB1

Sujet:

Description: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218).

Gene: SCARB1

Poids moléculaire: 61kDa

ID gène: 949

UniProt: Q8WTV0

Pathways: Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome