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PAR1 anticorps (N-Term)

F2R Reactivité: Humain, Rat, Souris WB, ELISA, IHC, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6265563
  • Antigène Voir toutes PAR1 (F2R) Anticorps
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    Épitope
    • 15
    • 15
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 68
    • 24
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Rat, Souris
    Hôte
    • 61
    • 7
    • 2
    Lapin
    Clonalité
    • 64
    • 6
    Polyclonal
    Conjugué
    • 39
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PAR1 est non-conjugé
    Application
    • 60
    • 35
    • 13
    • 13
    • 10
    • 8
    • 8
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    Thrombin Receptor Antibody detects endogenous levels of total Thrombin Receptor.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human Thrombin Receptor, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product F2R Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Zhao, Zheng, Liu, Luo, Wu, Liu, Zou: "Inhibiting trophoblast PAR-1 overexpression suppresses sFlt-1-induced anti-angiogenesis and abnormal vascular remodeling: a possible therapeutic approach for preeclampsia." dans: Molecular human reproduction, Vol. 24, Issue 3, pp. 158-169, (2018) (PubMed).

    Zhong, Chen, Zhang, Xiao, Qin, Gu, Sun, Liu, Jing, Hu, Zhang, Zhou, Sun, Yang: "Doxycycline directly targets PAR1 to suppress tumor progression." dans: Oncotarget, Vol. 8, Issue 10, pp. 16829-16842, (2017) (PubMed).

  • Antigène
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    Autre désignation
    F2R (F2R Produits)
    Synonymes
    anticorps CF2R, anticorps HTR, anticorps PAR-1, anticorps PAR1, anticorps TR, anticorps Par1, anticorps TRGPC, anticorps AI482343, anticorps Cf2r, anticorps ThrR, anticorps Par-1, anticorps f2r-a, anticorps par1, anticorps coagulation factor II thrombin receptor, anticorps coagulation factor II (thrombin) receptor, anticorps coagulation factor 2 (thrombin) receptor L homeolog, anticorps F2R, anticorps F2r, anticorps f2r.L
    Sujet

    Description: High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

    Gene: F2R

    Poids moléculaire
    48kDa
    ID gène
    2149
    UniProt
    P25116
    Pathways
    Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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