TRAF1 anticorps (C-Term)

N° du produit ABIN6265702

Détail du produit anti-TRAF1 anticorps

Antigène: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: TRAF1 Antibody detects endogenous levels of total TRAF1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TRAF1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TRAF1

Antigène: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Autre désignation: TRAF1 (TRAF1 Produits)

Synonymes: anticorps CG3048, anticorps DTRAF, anticorps DTRAF1, anticorps Dmel\\CG3048, anticorps TRAF, anticorps TRAF1, anticorps Traf1, anticorps dTRAF, anticorps dTRAF1, anticorps dTraf1, anticorps dtraf1, anticorps traf1, anticorps traf4, anticorps DKFZp469G032, anticorps EBI6, anticorps MGC:10353, anticorps 4732496E14Rik, anticorps TNF receptor associated factor 1, anticorps TNF-receptor-associated factor 4, anticorps TNF receptor-associated factor 1, anticorps TRAF1, anticorps Traf4, anticorps Traf1, anticorps traf1

Sujet:

Description: Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

Gene: TRAF1

Poids moléculaire: 46 kDa

ID gène: 7185

UniProt: Q13077

Pathways: Signalisation NF-kappaB, Apoptose, Cell-Cell Junction Organization, Asymmetric Protein Localization