ARFGAP3 anticorps (Internal Region)

N° du produit ABIN6282789

Détail du produit anti-ARFGAP3 anticorps

Antigène: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Épitope: AA 280-360, Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARFGAP3 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: ARF GAP3 is a protein encoded by the ARFGAP3 gene which is approximately 56,9 kDa. ARF GAP3 is localised to the cytoplasm and Golgi apparatus membrane. It is involved in transport to the Golgi and subsequent modification, Golgi-to-ER retrograde transport and metabolism of proteins. It associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. ARF GAP3 is widely expressed with the highest expression in endocrine glands and testis. Mutations in the ARFGAP3 gene result in premature menopause. STJ91672 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ARF GAP3 protein.

Specificité: ARF GAP3 Polyclonal Antibody detects endogenous levels of ARF GAP3 protein.

Attributs du produit: Rabbit polyclonal to ARF GAP3.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human ARF GAP3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
ELISA 1:10000

Commentaires:

Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur ARFGAP3

Antigène: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Autre désignation: ARF GAP3 (ARFGAP3 Produits)

Synonymes: anticorps ARFGAP1, anticorps 0610009H19Rik, anticorps 1810004P07Rik, anticorps 1810035F16Rik, anticorps 9130416J18Rik, anticorps Arfgap1, anticorps arfgap1, anticorps xgap, anticorps zgc:85765, anticorps arfgap3, anticorps ADP ribosylation factor GTPase activating protein 3, anticorps ADP-ribosylation factor GTPase activating protein 3, anticorps ADP ribosylation factor GTPase activating protein 3 S homeolog, anticorps ARFGAP3, anticorps Arfgap3, anticorps arfgap3, anticorps arfgap3.S

Poids moléculaire: 60 kDa

ID gène: 26286

UniProt: Q9NP61