KRT81 anticorps

N° du produit ABIN6292166

Détail du produit anti-KRT81 anticorps

Antigène: KRT81 (Keratin 81 (KRT81))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KRT81 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant Protein of human KRT81

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Abundantly expressed in the differentiating cortex of growing (anagen) hair, Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla, Expressed in malignant lymph node tissue in breast carcinoma tissue

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur KRT81

Antigène: KRT81 (Keratin 81 (KRT81))

Autre désignation: KRT81 (KRT81 Produits)

Synonymes: anticorps KRT81, anticorps KRTHB5, anticorps HB1, anticorps Hb-1, anticorps KRTHB1, anticorps MLN137, anticorps ghHkb1, anticorps hHAKB2-1, anticorps AA589625, anticorps Krt2-19, anticorps keratin 81, anticorps keratin, type II cuticular Hb1, anticorps keratin 85, anticorps KRT81, anticorps LOC100012075, anticorps LOC100092864, anticorps LOC100394162, anticorps LOC100481102, anticorps LOC100526784, anticorps KRT85, anticorps Krt81

Sujet: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle, this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.

Poids moléculaire: 54.928 kDa

ID gène: 3887

UniProt: Q14533