GZMB anticorps (AA 73-187)

N° du produit ABIN6294582

Cet anticorps anti-GZMB est un anticorps Lapin Polyclonal détectant GZMB dans WB, IHC, FACS et IF. Adapté pour Humain.

Aperçu rapide pour GZMB anticorps (AA 73-187) (ABIN6294582)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-GZMB anticorps

Épitope: AA 73-187

Fonction: Rabbit anti-Human Granzyme B Antibody [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: A recombinant fragment (amino acids 73-187) from the human protein was used as the immunogen for the Granzyme B antibody.

Immunogène: A recombinant fragment (amino acids 73-187) from the human protein was used as the immunogen for the Granzyme B antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: Granzyme B

Sujet:

Target Description: Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'non-self' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease.

Gene Symbol: GZMB///CGL1///CSPB///CTLA1///GRB

ID gène: 3002

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis