CD3 epsilon anticorps

N° du produit ABIN6296157

Cet anticorps anti-CD3 epsilon Polyclonal Lapin (ABIN6296157) détecte spécifiquement CD3 epsilon dans FACS, WB et IP. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Porc, Boeuf (Vache), Cheval, Lapin, Cobaye, Poulet, Chien, Mouton, Hamster, Cat, Cryptomys amatus (Mole rat), Elephant, Grenouille, Opossum et Primate.

Aperçu rapide pour CD3 epsilon anticorps (ABIN6296157)

Antigène: CD3 epsilon (CD3E)

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Cheval, Lapin, Cobaye, Poulet, Chien, Mouton, Hamster, Cat, Cryptomys amatus (Mole rat), Elephant, Grenouille, Opossum, Primate

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD3 epsilon est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-CD3 epsilon anticorps

Fonction: Rabbit anti-Human/Mouse/Rat/Primate/Guinea Pig/Hamster/Horse/Mole Rat/Pig/Rabbit/Sheep/Cat/Chicken/Cow/Dog/Frog/Opossum/Elephant CD3e Antibody [Sodium Azide Free]

Specificité: Cell surface and cytoplasmic

Purification: Amino acids ERPPPVPNPDYEP (156-168) were used as the immunogen for this CD3e antibody.

Immunogène: Amino acids ERPPPVPNPDYEP (156-168) were used as the immunogen for this CD3e antibody.

Information d'application

Indications d'application: FACS: use the CD3e antibody at 0.5-1 μg/million cells
WB: 0.5-1.0 μg/mL
IP: 1-2 μg/500 μg protein lysate,

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD3 epsilon

Antigène: CD3 epsilon (CD3E)

Autre désignation: T-cell surface glycoprotein CD3 epsilon chain

Sujet:

Target Description: This antibody recognizes the epsilon-chain of CD3 (CD3e), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the Tcell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the Tcell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the Tcell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the Tcell surface. CD3 antigen is a highly specific marker for Tcells, and is present in majority of Tcell neoplasms.

Gene Symbol: CD3E///T3E

ID gène: 916

UniProt: P07766

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway