CTNNB1 anticorps

N° du produit ABIN6296227

Cet anticorps Souris Monoclonal détecte spécifiquement CTNNB1 dans WB, IHC, IF et FACS. Il présente une réactivité envers Humain, Chien, Poulet et Boeuf (Vache).

Aperçu rapide pour CTNNB1 anticorps (ABIN6296227)

Antigène: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Reactivité: Humain, Chien, Poulet, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTNNB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-CTNNB1 anticorps

Fonction: Mouse anti-Human/Cow/Dog/Chicken Beta Catenin Antibody [Sodium Azide Free]

Specificité: Cell surface, cytoplasmic, cell junctions

Purification: Chicken beta-Catenin was used as the immunogen for the b-Catenin antibody.

Immunogène: Chicken beta-Catenin was used as the immunogen for the b-Catenin antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CTNNB1

Antigène: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Autre désignation: Catenin beta-1

Sujet:

Target Description: Beta Catenin is a dual function protein, regulating the coordination of cell -cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. b-Catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to gamma-Catenin, also known as plakoglobin. b-Catenin is widely expressed in many tissues. In cardiac muscle, it localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocyte. [Wiki]

Gene Symbol: CTNNB1///CTNNB///OK///SW-cl.35///PRO2286

ID gène: 1499

UniProt: P35222

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2