CD36 anticorps

N° du produit ABIN6296379

Cet anticorps anti-CD36 est un anticorps Souris Monoclonal détectant CD36 dans FACS, IF, ELISA et Func. Adapté pour Humain.

Aperçu rapide pour CD36 anticorps (ABIN6296379)

Antigène: CD36

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD36 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Functional Studies (Func)

Détail du produit anti-CD36 anticorps

Fonction: Mouse anti-Human CD36 Antibody [Sodium Azide Free]

Specificité: Cell surface

Purification: Human CD36 from platelets was used as the immunogen for the CD36 antibody.

Immunogène: Human CD36 from platelets was used as the immunogen for the CD36 antibody.

Information d'application

Indications d'application: Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL,ELISA: order the BSA free format

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD36

Antigène: CD36

Autre désignation: Platelet glycoprotein 4

Sujet:

Target Description: Recognizes a protein of 80 kDa-90 kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4 % of Japanese and East Asia population lack CD36.

Gene Symbol: CD36///GP3B///GP4

ID gène: 948

UniProt: P16671

Pathways: Signalisation TLR, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins