NADPH Oxidase 4 anticorps

N° du produit ABIN6296588

L’anticorps Souris Monoclonal anti-NADPH Oxidase 4 a été validé pour WB, ELISA, FACS, IF et Coat. Il convient pour détecter NADPH Oxidase 4 dans des échantillons de Humain.

Aperçu rapide pour NADPH Oxidase 4 anticorps (ABIN6296588)

Antigène: NADPH Oxidase 4 (NOX4)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NADPH Oxidase 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)

Détail du produit anti-NADPH Oxidase 4 anticorps

Fonction: Mouse anti-Human NOX4 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic and cell surface

Purification: Human recombinant protein was used as the immunogen for this NOX4 antibody.

Immunogène: Human recombinant protein was used as the immunogen for this NOX4 antibody.

Information d'application

Indications d'application: FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 1-2 μg/mL,ELISA: suitable, order BSA-free formulation for coating
WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur NADPH Oxidase 4

Antigène: NADPH Oxidase 4 (NOX4)

Autre désignation: NADPH oxidase 4

Sujet:

Target Description: The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.

Gene Symbol: NOX4///RENOX

ID gène: 4821

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration