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RNMT anticorps Primary Antibody

Reactivité: Boeuf (Vache), Chien, Humain, Rat IHC Hôte: Souris Monoclonal
N° du produit ABIN6297574
$530.20
Plus shipping costs $45.00
7 mL
local_shipping Destination: Etats-Unis
Envoi sous 6 à 8 jours ouvrables
  • Antigène
    Reactivité
    Boeuf (Vache), Chien, Humain, Rat
    Hôte
    Souris
    Clonalité
    Monoclonal
    Application
    Immunohistochemistry (IHC)
    Fonction
    Mouse anti-Human/Cow/Dog/Rat TAG-72 Antibody [IHC only]
    Specificité
    Cytoplasmic and cell surface
    Purification
    Recombinant human TAG-72 protein was used as the immunogen for this antibody.
    Immunogène
    Recombinant human TAG-72 protein was used as the immunogen for this antibody.
  • Antigène
    Autre désignation
    mRNA cap guanine-N7 methyltransferase  
    Sujet

    Target Description: This antibody recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 antibody with a GCDFP-15 antibody is valuable in the diagnosis of apocrine carcinoma.

    Gene Symbol: tag-72  C25A1.3

    ID gène
    182875
    UniProt
    Q9XVS1
  • Indications d'application
    Prediluted format : incubate for 30 min at RT (2)
    Restrictions
    For Research Use only
  • Buffer
    Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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