HAX1 anticorps (Middle Region)

N° du produit ABIN631119

Cet anticorps anti-HAX1 Polyclonal Lapin (ABIN631119) détecte spécifiquement HAX1 dans WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour HAX1 anticorps (Middle Region) (ABIN631119)

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAX1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HAX1 anticorps

Épitope: Middle Region

Specificité: HAX1 antibody was raised against the middle region of HAX1

Purification: Affinity purified

Immunogène: HAX1 antibody was raised using the middle region of HAX1 corresponding to a region with amino acids LPGPESETPGERLREGQTLRDSMLKYPDSHQPRIFGGVLESDARSESPQP

Information d'application

Indications d'application: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

HAX1 Blocking Peptide, (ABIN5613936), is also available for use as a blocking control in assays to test for specificity of this HAX1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HAX1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur HAX1

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Autre désignation: HAX1

Sujet: HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease.

Poids moléculaire: 31 kDa (MW of target protein)

Pathways: Regulation of Actin Filament Polymerization